CFDB - Cystic Fibrosis DataBase

ongoing trials trial from www.clinicaltrials.gov

Pilot E2 for Hypogonadal Women With CFBD - Phase 4 - Not yet recruiting

Study design (if review, criteria of inclusion for studies)

Interventional - Allocation: Randomized|Intervention Model: Parallel Assignment|Masking: Double (Participant, Outcomes Assessor)|Primary Purpose: Treatment

Participants

Cystic Fibrosis Related Bone Disease - 18 Years and older   (Adult, Older Adult)

Interventions

Drug: Estradiol 2 mg|Other: Placebo

Outcome measures

Change in serum estradiol level in picograms per milliliter (pg/mL) from baseline to 6 months among the treatment and placebo groups|Change in Serum carboxy-terminal collagen crosslinks (CTX-1) from baseline to 6 months among the treatment and placebo groups|change in of Serum Procollagen I Intact N-Terminal (P1NP) measured in mcg/L from baseline to 6 months among the treatment and placebo groups|Change in Cystic Fibrosis Questionnaire-Revised (CFQ-R) respiratory score from baseline to 6 months among the treatment and placebo groups|Change in percentage of FEV1 from baseline to 6 months among the treatment and placebo groups

Keywords: estrogens; estradiol; Hormones; pharmacological_intervention;