Welcome in CFDB (Cystic Fibrosis DataBase)!
This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.
You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.
Objective of CFDB (Cystic Fibrosis DataBase)
CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:
- which interventions are effective, in which groups of CF patients and for which outcomes?
- to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?
This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.
Latest articles
Antibiotic treatment for nonâtuberculous mycobacteria lung infection in people with cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2025
- Jahnke N
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2025
- Hurley Matthew N
Efficacy of Adding Oral N acetyl Cysteine Supplement to the Cystic Fibrosis Treatment Regimen: A Randomized Quasi-Experimental Trial.
primary studies published RCT
Details- 2025
- Keshavarz S
Elexacaftor/tezacaftor/ivacaftor in children aged â¥6â years with cystic fibrosis heterozygous for F508del and a minimal function mutation: Results from a 96-week open-label extension study.
primary studies published RCT
Details- 2025
- Mall MA
The Effects of Progressive Muscle Relaxation on Mental Health and Sleep Quality in Adults with Cystic Fibrosis: A Randomized Controlled Trial.
primary studies published RCT
Details- 2025
- Maritescu A
Effects of Oral Amino Acid Supplementation on Physical Activity, Systemic Inflammation, and Quality of Life in Adult Patients with Cystic Fibrosis: A Single-Center, Randomized, Double-Blind, Placebo-Controlled Pilot Study.
primary studies published RCT
Details- 2025
- Petraglia L
A Phase 3, Open-label Study Evaluating the Long term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects 12 Months of Age and Older
ongoing trials trial from other registries
Details- 2024