CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,500 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Dornase alfa for cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2021
  • Yang Connie

Timing of dornase alfa inhalation for cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2021
  • Dentice Ruth

Nasal high-flow therapy as an adjunct to exercise in patients with cystic fibrosis: A pilot feasibility trial.

primary studies published RCT

Details
  • 2021
  • Spoletini G

Efficacy and safety of inhaled dry-powder mannitol in adults with cystic fibrosis: An international, randomized controlled study.

primary studies published RCT

Details
  • 2021
  • Flume PA

Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor for 24 Weeks or Longer in People with Cystic Fibrosis and One or More F508del Alleles: Interim Results of an Open-Label Phase 3 Clinical Trial.

primary studies published RCT

Details
  • 2021
  • Griese M

Reflex zone stimulation reduces ventilation inhomogeneity in cystic fibrosis: A randomised controlled cross-over study.

primary studies published RCT

Details
  • 2021
  • Jana P

The benefits of mechanical insufflator-exsufflator compared to autogenic drainage in adults with cystic fibrosis.

primary studies published RCT

Details
  • 2020
  • Helper N