CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,500 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2016
  • Regan Kate

Clustered randomized controlled trial of a clinic-based problem-solving intervention to improve adherence in adolescents with cystic fibrosis.

primary studies published RCT

Details
  • 2019
  • Quittner AL

Supporting medication adherence for adults with cystic fibrosis: a randomised feasibility study.

primary studies published RCT

Details
  • 2019
  • Hind D

Effects of inspiratory muscle training on postural stability, pulmonary function and functional capacity in children with cystic fibrosis: A randomised controlled trial.

primary studies published RCT

Details
  • 2019
  • Zeren M

A Phase 2 Study to Evaluate Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis - Phase 2 - Not yet recruiting

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2019
  • Vertex Pharmaceuticals Incorporated

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis - Phase 2 - Not yet recruiting

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2019
  • Vertex Pharmaceuticals Incorporated

A Study to Evaluate Safety and Efficacy of Subcutaneous Administration of Anakinra in Patients With CF - Phase 2 - Not yet recruiting

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2019
  • Heidelberg University