CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,500 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Single versus combination intravenous anti-pseudomonal antibiotic therapy for people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2021
  • Holland P

Drug therapies for reducing gastric acidity in people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2021
  • Ng Sze May

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Protocol (ongoing review)

Details
  • 2021
  • Pereira NP

Body composition and weight changes after ivacaftor treatment in adults with cystic fibrosis carrying the G551 D cystic fibrosis transmembrane conductance regulator mutation: A double-blind, placebo-controlled, randomized, crossover study with open-label extension.

primary studies published RCT

Details
  • 2021
  • King SJ

Randomized, Controlled Trial Of Sitagliptin And Islet Function In Cystic Fibrosis With Abnormal Glucose Tolerance.

primary studies published RCT

Details
  • 2021
  • Kelly A

Ivacaftor in cystic fibrosis with residual function: Lung function results from an N-of-1 study.

primary studies published RCT

Details
  • 2020
  • Nick JA

Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/Navocaftor/ABBV-119 Combination Therapy in Adult Participants With Cystic Fibrosis - Phase 2 - Not yet recruiting

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2021
  • AbbVie