CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 2,000 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Lack of efficacy of Lactobacillus GG in reducing pulmonary exacerbations and hospital admissions in children with cystic fibrosis: A randomised placebo controlled trial.

primary studies published RCT

Details
  • 2017
  • Bruzzese E

Bolus weekly vitamin D3 supplementation impacts gut and airway microbiota in adults with cystic fibrosis: a double-blind, randomized, placebo-controlled clinical trial.

primary studies published RCT

Details
  • 2017
  • Kanhere M

Combined Dry Powder Tobramycin and Nebulized Colistin Inhalation in CF Patients - Phase 3 - Completed

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2014
  • University Hospital Tuebingen

Physical exercise training for cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2017
  • Radtke T

Palliative drug treatments for breathlessness in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2017
  • Jaiswal N

Autogenic drainage for airway clearance in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2017
  • McCormack Pamela

In vivo and in vitro ivacaftor response in cystic fibrosis patients with residual CFTR function: N-of-1 studies.

primary studies published RCT

Details
  • 2017
  • McGarry ME