CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 2,000 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Autogenic drainage for airway clearance in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2017
  • McCormack Pamela

Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2017
  • Waters Valerie

Ursodeoxycholic acid for cystic fibrosis-related liver disease

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2017
  • Cheng Katharine

Interventions for managing advanced liver disease in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2017
  • Palaniappan SK

Tezacaftor/Ivacaftor in Subjects with Cystic Fibrosis and F508del/F508del-CFTR or F508del/G551D-CFTR.

primary studies published RCT

Details
  • 2017
  • Donaldson SH

Chest physiotherapy can affect the lung clearance index in cystic fibrosis patients.

primary studies published RCT

Details
  • 2017
  • Grosse-Onnebrink J

Randomized, Double-Blind, Phase 3B Trial to Evaluate the Safety and Efficacy of 2 Treatment Regimens of Aztreonam 75 mg Powder and Solvent for Nebulizer Solution / Aztreonam for Inhalation Solution (AZLI) in Pediatric Subjects with Cystic Fibrosis (CF) and New Onset Respiratory Tract Pseudomonas aeruginosa (PA) Infection/Colonization

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2016