CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,500 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Antioxidant supplementation for lung disease in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2019
  • Ciofu O

Medical interventions for chronic rhinosinusitis in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2019
  • Karanth TK

A smartphone application for reporting symptoms in adults with cystic fibrosis improves the detection of exacerbations: Results of a randomised controlled trial.

primary studies published RCT

Details
  • 2019
  • Wood J

Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.

primary studies published RCT

Details
  • 2019
  • Heijerman HGM

Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.

primary studies published RCT

Details
  • 2019
  • Middleton PG

Acceptance and Commitment Therapy vs. Supportive Psychotherapy With Cystic Fibrosis Patients - Not Applicable - Recruiting

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2019
  • Drexel University

Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis - Phase 4 - Not yet recruiting

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2019
  • Emory University