CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,500 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Drug treatments for managing cystic fibrosis‐related diabetes

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2020
  • Onady Gary M

Prophylactic anti-staphylococcal antibiotics for cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2020
  • Rosenfeld M

Does synbiotic supplementation affect the quality of life in children with cystic fibrosis? A pilot randomized controlled clinical trial.

primary studies published RCT

Details
  • 2020
  • Bilan N

Ivacaftor in People With Cystic Fibrosis and a 3849+10kb C →T or D1152H Residual Function Mutation.

primary studies published RCT

Details
  • 2020
  • Kerem E

Effects of music therapy as an adjunct to chest physiotherapy in children with cystic fibrosis: A randomized controlled trial.

primary studies published RCT

Details
  • 2020
  • Montero-Ruiz A

Chest computed tomography outcomes in a randomized clinical trial in cystic fibrosis: Lessons learned from the first ataluren phase 3 study.

primary studies published RCT

Details
  • 2020
  • Tiddens HAWM

CFTR activity is enhanced by the novel corrector GLPG2222, given with and without ivacaftor in two randomized trials.

primary studies published RCT

Details
  • 2019
  • Bell SC