Study design (if review, criteria of inclusion for studies)
Randomized controlled trial.
Participants
Adults with cystic fibrosis (CF). 23 participants (age 32.13â±â7.72âyears).
Interventions
A remotely supervised, individualized 8-week resistance training program of moderate to high intensity. The exercise group (EX) performed three 1-h resistance training sessions per week over 8âweeks. The control group (CON) followed the physical activity recommendations of their physician.
Outcome measures
The main outcomes were muscle strength and body composition, with secondary measures including pulmonary function and quality of life. Two-way repeated measures analysis was used.
Main results
In 23 participants (age 32.13â±â7.72âyears), the intervention showed a significant beneficial effect on leg press strength, with a large effect size, both in absolute (pâ=â0.011; ηp2 â=â0.281) and relative (pâ=â0.007; ηp2 â=â0.310) terms. Large intervention effects were observed on total fat mass (pâ<â0.001; ηp2 â=â0.415), body adiposity index (pâ<â0.001; ηp2 â=â0.436), and fat mass index (pâ<â0.001; ηp2 â=â0.445), all showing reduction in the EX group. In addition, significant large size effects were detected on total fat-free mass (pâ=â0.046; ηp2 â=â0.177), trunk fat-free mass (pâ=â0.039; ηp2 â=â0.188), and fat-free mass index (pâ=â0.048; ηp2 â=â0.174), all favoring exercise. No significant effects were observed on pulmonary function and quality of life.
Authors' conclusions
An 8-week remotely supervised resistance training program, with moderate to high intensity, effectively improved lower limb muscle strength and body composition.