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primary studies published RCT

Comparative trial between two pancreatine in enteric coated microspheres preparations in children with cystic fibrosis and steatorrhoea.

  • Year: 1990
  • Date: 1990
  • Author: Lazaro A
Source

BoletÝn de la Sociedad de PediatrÝa de Arag¾n, La Rioja y Soria YR: 1990 VL: 20 DE: RCT

Study design (if review, criteria of inclusion for studies)

randomized cross-over study

Participants

children with cystic fibrosis and steatorrhoea

Interventions

Kreon and Pancrease used to the same dose

Outcome measures

safety and efficacy

Main results

The efficacy were similar in both preparations, although Kreaon normalized in a bigger percentage of patients the values of fatty neuter, fatty acid and quimiotripsine in lees/24h. Both preparations showed excellent tolerance and clinical security.

Authors' conclusions

Both preparations showed excellent tolerance and clinical security.

Keywords: Child; Microspheres; pharmacological_intervention; Pancreatic Enzyme Replacement Therapy; Pancreas insufficiency; Pancreatic Diseases; Gastrointestinal Diseases; Malabsorption; Nutrition Disorders; Enteric-Coated; Gastrointestinal Agents;