CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Corrector therapies (with or without potentiators) for people with cystic fibrosis with class II CFTR gene variants (most commonly F508del)

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2023
  • Southern KW

Nebuliser systems for drug delivery in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2023
  • Daniels Tracey

Surgery for nasal polyposis in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2023
  • Ribeiro LA

The cost of simplifying treatments for cystic fibrosis: Implications of the SIMPLIFY trial.

primary studies published RCT

Details
  • 2024
  • Gold LS

Randomized Trial of the Insulin-Only iLet Bionic Pancreas for the Treatment of Cystic Fibrosis- Related Diabetes.

primary studies published RCT

Details
  • 2023
  • Sherwood JS

SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes - Phase 2|Phase 3 - Not yet recruiting

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2023
  • Amir Moheet|University of Minnesota

A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis - Phase 1|Phase 2 - Not yet recruiting

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2023
  • Clarametyx Biosciences, Inc.