CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Inhaled anti-pseudomonal antibiotics for long-term therapy in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2022
  • Smith S

Appetite stimulants for people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2022
  • McTavish D

Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2022
  • Francis NZ

Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials.

primary studies published RCT

Details
  • 2022
  • Mayer-Hamblett N

Airway clearance physiotherapy and health-related quality of life in cystic fibrosis.

primary studies published RCT

Details
  • 2022
  • Gursli S

Challenged Urine Bicarbonate Excretion as a Measure of Cystic Fibrosis Transmembrane Conductance Regulator Function in Cystic Fibrosis.

primary studies published, non RCT

Details
  • 2022
  • Berg P

The long-term effects of insulin use in incident cystic fibrosis-related diabetes: a target trial emulated using longitudinal national registry data.

primary studies published, non RCT

Details
  • 2022
  • Granger E