Welcome in CFDB (Cystic Fibrosis DataBase)!
This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.
You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.
Objective of CFDB (Cystic Fibrosis DataBase)
CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:
- which interventions are effective, in which groups of CF patients and for which outcomes?
- to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?
This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.
Latest articles
Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2025
- Calthorpe R
Non-invasive ventilation for cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2025
- AS Sousa
Impact of telenursing-based family empowerment program on self-efficacy and treatment adherence in children with cystic fibrosis "telenursing and CF".
primary studies published RCT
Details- 2026
- Rameh F
Safety, feasibility and efficacy of exercise as an airway clearance technique in cystic fibrosis: a randomised pilot feasibility trial.
primary studies published RCT
Details- 2026
- Urquhart DS
Providing Mobile Patient Access to Their Electronic Secondary Care Patient Record in Adults With Cystic Fibrosis: Results of a Prospective, Parallel, Randomized Open-Pilot Quantitative Study.
primary studies published RCT
Details- 2025
- Chadwick HK
Impact of Elexacaftor/Tezacaftor/Ivacaftor on Glucose Tolerance and Abnormal Glucose Metabolism: A Phase 3b, Open-Label Clinical Trial.
primary studies published RCT
Details- 2025
- Durieu I
Effect of elexacaftor-tezacaftor-ivacaftor on bronchial dilatations in adolescents with cystic fibrosis: a multicentre prospective observational study.
primary studies published, non RCT
Details- 2026
- Sermet-Gaudelus I