Welcome in CFDB (Cystic Fibrosis DataBase)!
This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.
You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.
Objective of CFDB (Cystic Fibrosis DataBase)
CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:
- which interventions are effective, in which groups of CF patients and for which outcomes?
- to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?
This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.
Latest articles
Antibiotic treatment for nonâtuberculous mycobacteria lung infection in people with cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2025
- Jahnke N
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2025
- Hurley Matthew N
Ivacaftor-tezacaftor-elexacaftor, tezacaftor-ivacaftor and lumacaftor-ivacaftor for treating cystic fibrosis: a systematic review and economic evaluation.
HTA - Health Technology Assessment Report
Details- 2025
- Edwards SJ
Insulin for early glycaemic abnormality in children with cystic fibrosis without cystic fibrosis-related diabetes (CF-IDEA): a randomised controlled trial.
primary studies published RCT
Details- 2025
- Hameed S
The Effects of Progressive Muscle Relaxation on Mental Health and Sleep Quality in Adults with Cystic Fibrosis: A Randomized Controlled Trial.
primary studies published RCT
Details- 2025
- Maritescu A
20 years of the Montreal Cystic Fibrosis Related Diabetes Screening Cohort: key insights.
primary studies published, non RCT
Details- 2025
- Alexandre-Heymann L
A Phase 3, Open-label Study Evaluating the Long term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects 12 Months of Age and Older
ongoing trials trial from other registries
Details- 2024