CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Protocol (ongoing review)

Details
  • 2023
  • Jones M

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2023
  • Pereira NP

Effects of an early rehabilitation program for adult cystic fibrosis patients during hospitalization: a randomized clinical trial.

primary studies published RCT

Details
  • 2023
  • Flores J

Steps Ahead: Optimising physical activity in adults with cystic fibrosis: A pilot randomised trial using wearable technology, goal setting and text message feedback.

primary studies published RCT

Details
  • 2023
  • Curran M

Embedded Specialist Palliative Care in Cystic Fibrosis: Results of a Randomized Feasibility Clinical Trial.

primary studies published RCT

Details
  • 2023
  • Kavalieratos D

Emulated trial investigating effects of multiple treatments: estimating combined effects of mucoactive nebulisers in cystic fibrosis using registry data.

primary studies published, non RCT

Details
  • 2023
  • Granger E

Impact of lumacaftor/ivacaftor and tezacaftor/ivacaftor on treatment response in pulmonary exacerbations of F508del/F508del cystic fibrosis.

primary studies published, non RCT

Details
  • 2023
  • McElvaney OJ