Welcome in CFDB (Cystic Fibrosis DataBase)!
This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.
You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.
Objective of CFDB (Cystic Fibrosis DataBase)
CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:
- which interventions are effective, in which groups of CF patients and for which outcomes?
- to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?
This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.
Latest articles
Active cycle of breathing technique for cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2023
- Wilson LM
Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2023
- Smith S
Treatment of chronic rhinosinusitis with dornase alfa in patients with cystic fibrosis: a systematic review.
Other Reviews - Other Review
Details- 2018
- Shah GB
Effects of Lumacaftor/Ivacaftor on Cystic Fibrosis Disease Progression in Children 2 through 5 Years of Age Homozygous for F508del-CFTR: A Phase 2 Placebo-controlled Clinical Trial.
primary studies published RCT
Details- 2023
- Stahl M
A prospective randomised controlled mixed-methods pilot study of home monitoring in adults with cystic fibrosis.
primary studies published RCT
Details- 2022
- Nash EF
Newborn screening alone insufficient to improve pulmonary outcomes for cystic fibrosis.
primary studies published, non RCT
Details- 2021
- Barreda CB
Feasibility and acceptability of a CF-specific cognitive-behavioral preventive intervention for adults integrated into team-based care.
primary studies published, non RCT
Details- 2022
- Friedman D