CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Short‐acting inhaled bronchodilators for cystic fibrosis.

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2022
  • Smith S

Exercise versus airway clearance techniques for people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2022
  • Patterson KD

Surgery for nasal polyposis in cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Protocol (ongoing review)

Details
  • 2022
  • Ribeiro LA

Dietary interventions for managing glucose abnormalities in people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Protocol (ongoing review)

Details
  • 2022
  • Birch L

Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3B, Randomized, Placebo-Controlled Study.

primary studies published RCT

Details
  • 2022
  • Mall MA

Feasibility and efficacy of combined pancreatic islet-lung transplantation in cystic fibrosis related diabetes -PIM study: a multicenter phase 1-2 trial.

primary studies published, non RCT

Details
  • 2022
  • Rakotoarisoa L

A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa - Phase 1|Phase 2 - Not yet recruiting

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2022
  • National Institute of Allergy and Infectious Diseases (NIAID)