Welcome in CFDB (Cystic Fibrosis DataBase)!
This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.
You'll find more than 1,500 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.
Objective of CFDB (Cystic Fibrosis DataBase)
CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:
- which interventions are effective, in which groups of CF patients and for which outcomes?
- to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?
This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.
Latest articles
Recombinant growth hormone therapy for cystic fibrosis in children and young adults
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2018
- Thaker V
Timing of pancreatic enzyme replacement therapy (PERT) in cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2019
- Ng C
GLPG2737 in lumacaftor/ivacaftor-treated CF subjects homozygous for the F508del mutation: A randomized phase 2A trial (PELICAN).
primary studies published RCT
Details- 2020
- van Koningsbruggen-Rietschel S
Association Between Transient Elastography and Controlled Attenuated Parameter and Liver Ultrasound in Children With Cystic Fibrosis.
primary studies published, non RCT
Details- 2021
- Ye W
A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection - Phase 2|Phase 3 - Recruiting
ongoing trials trial from www.clinicaltrials.gov
Details- 2021
- Bambino Gesù Hospital and Research Institute|University of Exeter|Radboud University|Consorzio per Valutazioni Biologiche e Farmacologiche
Nebulized Bacteriophage Therapy in Cystic Fibrosis Patients With Chronic Pseudomonas Aeruginosa Pulmonary Infection - Phase 1|Phase 2 - Not yet recruiting
ongoing trials trial from www.clinicaltrials.gov
Details- 2021
- BiomX, Inc.
A randomized, open-label, active controlled, parallel group, multicenter phase 3 study to evaluate the efficacy and tolerability of Bamlanivimab and Etesevimab, Casirivimab and Imdevimab, and Sotrovimab versus Standard of Care in patients with mild to moderate COVID-19 disease (AntiCov)
ongoing trials trial from other registries
Details- 2021