Welcome in CFDB (Cystic Fibrosis DataBase)!
This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.
You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.
Objective of CFDB (Cystic Fibrosis DataBase)
CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:
- which interventions are effective, in which groups of CF patients and for which outcomes?
- to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?
This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.
Latest articles
Interventions for the eradication of methicillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2026
- Lo David KH
CFTR modulator monotherapy for people with cystic fibrosis with class II CFTR gene variants (most commonly F508del)
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2026
- Matthew Heneghan
Nucleic acidâbased therapies for people with cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Protocol (ongoing review)
Details- 2026
- Addy C
Prenatal CFTR modulator therapy and fetal meconium ileus in cystic fibrosis: a systematic review and individual patient data meta-analysis.
Other Reviews - Other Review
Details- 2026
- Menditto VG
The Impact of Exercise Intervention on Pulmonary and Physical Function in Patients With Cystic Fibrosis: A Comprehensive Systematic Review.
Other Reviews - Other Review
Details- 2026
- Alghamdi A
Postprandial ultra-fast insulin versus mealtime fast-acting insulin in adults with cystic fibrosis-related diabetes: A randomized multicentre crossover trial.
primary studies published RCT
Details- 2026
- Rakotoarisoa L
Feasibility and Impact of a Coached Home-Based Exercise Program on Cardiorespiratory Fitness in Adults With Cystic Fibrosis on Highly Effective Modulator Therapy.
primary studies published RCT
Details- 2026
- Barry A