Children with cystic fibrosis (CF) and chronic constipation -
Interventions
Maralixibat (a non-systemic bile acid transport inhibitor (IBATi) that acts by interrupting bile acid reabsorption in the ileum thus interrupting the normal enterohepatic circulation)
Outcome measures
consistency of stool to Bristol scale \>4
Keywords: Maralixibat; bile acid transport inhibitor; Laxatives; Gastrointestinal Agents; pharmacological_intervention;