Study design (if review, criteria of inclusion for studies)
randomised balanced design.
Participants
20 adult patients with stable cystic fibrosis
Interventions
ramped maximal treadmill test (STEEP protocol) and the MST
Outcome measures
comparing performance on the MST with peak oxygen consumption (VO2peak)
Main results
The relationship between the distance achieved on the MST and VO2peak was strong (r = 0.95, p<0.01) with 90% of the variance in VO2peak explained by the variance in MST distance. The relationship was represented by the regression equation (with 95% confidence intervals) VO2peak = 6.83 (2.85 to 10.80) + 0.028 (0.019 to 0.024) x MST distance.
Authors' conclusions
This study provides evidence of the construct validity of the MST as an objective measure of exercise capacity in adults with cystic fibrosis.