Study design (if review, criteria of inclusion for studies)
Randomised, cross-over trial
Participants
27 CF participants in stable condition
Interventions
Treatment A: diaphragm breathing with incentive spirometry and PD. Treatment B: diaphragm breathing with PEP and PDTreatments given in random order on different days with at least 48 hours washout in between.
Outcome measures
Sputum weight, lung function (FVC, FEV1, FEV1 %, MMEFwt-75, MVV, PF), questionnaire on frequency and intensity of coughing, sputum characteristics, chest discomfort, dyspnoea.
Main results
During treatment A with incentive spirometry, 14.6 +/- 13.7 g of sputum was removed, whereas 9.8 +/- 10.2 g was eliminated during treatment B (p < 0.05). The differences in PEF after treatments A and B in comparison with baseline values were +19.3 l/min and -0.2 l/min, respectively (p < 0.01). PEF stayed high during the afternoon, in comparison with baseline, with treatment A (p < 0.02). After treatment B, no changes in PEF in comparison with baseline were observed (p = 0.49). Neither treatment led to significant differences in symptoms reported on the clinical questionnaire.
Authors' conclusions
Respiratory physiotherapy with incentive spirometry significantly increases sputum clearance in cystic fibrosis patients, with no immediate repercussions on lung function or symptoms.