Bronchial artery embolization for hemoptysis in young patients with cystic fibrosis.
Year: 2002
Date: 2002
Author: Barben J
Source
Radiology. 2002 Jul;224(1):124-30.
Study design (if review, criteria of inclusion for studies)
review of 15-year experience by searching the 1985-1999 radiology database
Participants
23 young patients who had been referred to the radiology department for angiography.
Interventions
Bronchial artery embolization (BAE)
Outcome measures
The medical records were retrospectively reviewed with regard to embolization success rates, number of repeat embolizations, survival times, and causes of death.
Main results
BAE was performed on 38 occasions in 20 patients. The mean age of patients at first BAE was 15 years (age range, 7-19 years). The majority (n = 34 [89%]) of BAEs were performed by using polyvinyl alcohol. The immediate success rate after BAE (ie, no recurrent bleeding within 24 hours) was 95% (36 of 38 BAEs). Eleven (55%) patients required more than one BAE, and the median time between first and second embolizations was 4 months (range, 5 days to 61 months). Three patients died as a consequence of severe hemoptysis during induction of anesthesia with intermittent positive pressure ventilation in preparation for BAE. The median survival duration after the first BAE (Kaplan-Meier estimate) was 84 months (average follow-up, 61 months; range, 5 days to 169 months).
Authors' conclusions
BAE had a high success rate for short-term control of bleeding; however, more than half the patients required repeat embolization during the long-term follow-up.