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primary studies published RCT

Inspiratory muscle training improves lung function and exercise capacity in adults with cystic fibrosis.

  • Year: 2004
  • Date: 2004
  • Author: Enright S
Source

Chest. 2004 Aug;126(2):405-11.

Study design (if review, criteria of inclusion for studies)

Parallel design over 8 weeks.

Participants

All participants: n = 29, mean (SD) age = 22 (4.2) years. Intervention 1: n = 9, mean (SD) age = 24.8 (5.5) years. Intervention 2: n = 10, mean (SD) age = 20 (4.7) years. Control: n = 6, mean (SD) age = 21.3 (2.7) years.

Interventions

Control = "No Training" Intervention 1 = IMT at 80% of "maximal inspiratory effort". Intrevention 2 = IMT at 20% of "maximal inspiratory effort". IMT = Incremental maximal effort with progressively shorter rest periods, 3 times a week.

Outcome measures

FEV1(%pred), FVC (%pred), PImax, SPImax, heart rate, perceived exertion, dyspnoea and Chronic Respiratory Disease Questionnaire.

Main results

Following training, significant increases in Pimax and SPimax (p < 0.05), TDIcont (p < 0.05), TR (p < 0.05), vital capacity (p < 0.05), TLC (p < 0.05), and PWC (p < 0.05) were identified, and decreases in anxiety scores (p < 0.05) and depression scores (p < 0.01) were noted in group 1 patients compared to group 3 patients. Group 2 patients significantly improved Pimax and SPimax (both p < 0.05) only with respect to group 3 patients. No significant differences were observed in group 3 patients.

Authors' conclusions

An 8-week program of high-intensity IMT resulted in significant benefits for CF patients, which included increased IMF and thickness of the diaphragm (during contraction), improved lung volumes, increased PWC, and improved psychosocial status.

Related topics

Active cycle of breathing technique in cystic fibrosis

Oscillating devices in cystic fibrosis

Positive expiratory pressure in cystic fibrosis

Keywords: Adolescent; Adult; Inhalation OR nebulised; non pharmacological intervention - psyco-soc-edu-org; non pharmacological intervention - devices OR physiotherapy; pharmacological_intervention; training; inspiratory muscle training; exercise; Chest physiotherapy;