Study design (if review, criteria of inclusion for studies)
1-year randomized clinical trial.
Participants
67 patients with CF, aged 8 to 18 years
Interventions
Participants in both exercise conditions were encouraged to exercise at least three times per week for 1 year. Each child in the aerobic group was given a stair-stepping machine, and each child in the upper-body strength training group was given an upper-body-only weight-resistance machine. Counselors conducted in-home visits with the participants once per week for the first 8 weeks followed by monthly visits for the remainder of the study
Outcome measures
Aerobic fitness, pulmonary function, quality of life, and strength were measured at baseline, at 6 months, and at 12 months.
Main results
Strength training increased the maximum weight lifted for biceps curls significantly more than aerobic training (p < 0.02). However, this differential did not remain significant after control for increase in height. Both training procedures were associated with increased strength (p < 0.002) and physical work capacity (PWC) [p < 0.033].
Authors' conclusions
We concluded that strength and aerobic training may increase upper-body strength, and that both types of training may increase PWC for children with CF. Future trials should be conducted with no-training control subjects and larger samples to increase statistical power.