Subjects (n = 111) 3 weeks to 60 years of age were investigated.
Interventions
sweat test with Nanoduct or Macroduct
Outcome measures
sweat production, classic CF, healthy subjects
Main results
Three children had no sweat production, and in 14 children, only conductivity could be measured. In the remaining 94 subjects, the new system identified all patients with classic CF (mean conductivity, 115 mmol/L; range, 92 to 137) and differentiated them from healthy subjects (mean conductivity, 36 mmol/L; range, 17 to 59) within a mean time of 20 minutes.
Authors' conclusions
Measuring sweat conductivity using the new test system reliably differentiated between patients with and those without CF. This suggests that the new system could be used as a diagnostic test in addition to its suggested screening value.
Keywords: Adult; Child; Infant; Newborn; non pharmacological intervention - diagn;