Study design (if review, criteria of inclusion for studies)
Parallel design. Quasi-randomised controlled trial
Participants
< 90% ideal WFH or 5% reduction in ideal WFH over 3 months. CF participants aged >10 years. Age on entry to trial: advice group mean (SD) 16.4 years (6.7); supplement group mean (SD) 19.5 years (11.3). Most recent published report states 15 were enrolled but 2 dropped out. Although 2 out of 7 in the supplement group did not continue taking supplements, they were analysed as ITT
Interventions
Control group received nutritional counselling to increase energy intake by 20% of predicted energy needs by eating high calorie foods. Study period, 3 months. High calorie drink to increase energy intake by 20% of predicted energy needs
Outcome measures
Anthropometric measures* Z scores for weight* and height*, WFH* Pulmonary function* Energy* and nutrient* intake Faecal balance studies
Main results
There was no significant change in energy intake or percent ideal body weight in either group.