Study design (if review, criteria of inclusion for studies)
prospective, randomised controlled trial
Participants
75 people with cystic fibrosis
Interventions
different ACTs.
Outcome measures
The primary outcome measure was forced expiratory volume in one second (FEV(1)). Secondary outcome measures included exercise capacity and health related quality of life.
Main results
Using intention to treat, data were available on 65 subjects at the end of the study period. There were no statistically significant differences among the regimens in the primary outcome measurement of FEV(1) (p=0.35).
Authors' conclusions
In different countries either one or several airway clearance regimens are used. This study provides evidence in support of current practices.