Journal of Pediatric Gastroenterology and Nutrition YR: 1991 VL: 12 DE: RCT NO: 2

10 malnourished CF patients with moderate to severe lung disease. Their BEE before ingesting the supplements was 120% of that predicted by the Harris-Benedict equation.

low carbohydrate (Pulmocare) and higher carbohydrate (Instant Breakfast) nutritional supplements

VCO2, respiratory quotient (RQ), minute ventilation (VE), metabolic expenditure

Their VCO2 increased 9-19% for the 3h after ingesting 500 kcal/M2 of Pulmocare, and 25-30% after ingesting Instant Breakfast (p less than 0.05). The respiratory quotient (RQ) was significantly greater for Instant Breakfast than Pulmocare. The minute ventilation (VE) rose 10-13% for the 3h after ingesting Pulmocare, versus 27-31% after ingesting Instant Breakfast, but the difference was not significant. The metabolic expenditure rose 13-16% for the 3h after ingesting both formulas.

CF patients have increasing difficulty maintaining their nutrition as their pulmonary disease progresses

A, E, K vitamins supplementation

Agents which reduce gastric acidity in cystic fibrosis

Calorie supplements in cystic fibrosis

General nutrition recommendations in cystic fibrosis

Pancreatic enzyme replacement therapy in cystic fibrosis

Vitamin D supplementation