CFDB - Cystic Fibrosis DataBase

primary studies published, non RCT

Predigested formula for infants with cystic fibrosis.

Participants

19 newly diagnosed CF patients

Interventions

Pregestimil vs standard formula

Outcome measures

growth rates

Main results

At 1 year of age, the Pregestimil group showed significantly greater length and weight and a twofold higher average weight percentile. Growth velocity determined for the period between diagnosis and 12 months of age was better (p less than .001) for babies raised on Pregestimil (556 compared with 423 gm/month). Using weight percentile as the major growth index and values less than the fifth percentile as abnormal at age 12 months, we found that all 19 babies were normal in the group fed Pregestimil, whereas nine were below the fifth percentile in the group fed regular formula (p = .0006).

Keywords: Food; Infant; non pharmacological intervention - diet;