Study design (if review, criteria of inclusion for studies)
Single-site, equal-allocation randomized pilot study
50 Adults with CF age â¥18 years with any of the following: FEV(1)% predicted â¤50, â¥2 CF-related hospitalizations in the past 12 months, supplemental oxygen use, or noninvasive mechanical ventilation use, and moderate-or-greater severity of any symptoms on the Edmonton Symptom Assessment Scale. Mean age 38, baseline mean FEV(1)% predicted 41.8 (usual care), and 41.2 (intervention).
Authors randomized 50 adults with CF to intervention (nâ=â25) or usual care (nâ=â25),
Intervention visit completion, data completements, participant ratings of intervention acceptability and benefit, and intervention delivery fidelity.
No participants withdrew, five were lost to follow-up, and two died (88% retention). In the intervention group, 23 of 25 completed all study visits; 94% stated the intervention was not burdensome, and 97.6% would recommend the intervention to others with CF. More than 90% of study visits addressed topics prescribed by intervention manual.
Adding specialist PC to standard clinic visits for adults with CF is feasible and acceptable.