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primary studies published RCT

The long-term effect of elexacaftor/tezacaftor/ivacaftor on cardiorespiratory fitness in adolescent patients with cystic fibrosis: a pilot observational study.

  • Year: 2024
  • Date: 1988
  • Author: Stastna N
Source

BMC Pulm Med. 2024 May 28;24(1):260. doi: 10.1186/s12890-024-03069-8.

Study design (if review, criteria of inclusion for studies)

Randomized cross-over study.

Participants

Children and adults with CF (diagnosed with sweat test) with chronic P. aeruginosa needing IV antibiotics and living within a radius of 10 miles of the hospital.

Interventions

IV antibiotics (a ß-lactam and an aminoglycoside)

Outcome measures

Lung function, oxygen saturation, weight, psychological evaluations, ecomomic evaluations

Keywords: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Home; Home Care Services; Intravenous; non pharmacological intervention - psyco-soc-edu-org; pharmacological_intervention; Bacterial Infections; Respiratory Tract Infections; Respiratory Tract Diseases; Infection; Organization;