Study design (if review, criteria of inclusion for studies)
Systematic review and meta-analysis of randomized controlled trials
Participants
Patients with cystic fibrosis.
Interventions
Physical training and Pulmonary Rehabilitation
Outcome measures
Pulmonary function, exercise capacity
Main results
Twenty-three studies with a total of 800 patients with CF were included. This meta-analysis showed that pulmonary rehabilitation and physical training did not affect pulmonary function, as observed in FEV1 (SMD: 0.05; 95% CI: -0.09 to 0.20; p = 0.46) and FVC (SMD: 0.11; 95% CI: -0.04 to 0.27; p = 0.14). However, it has a discrete impact on exercise capacity, producing an increase in VO(2) max (MD: 2.74; 95% CI: 0.43 to 5.04; p = 0.02). Subgroup analyses did not yield relevant findings, and sensitivity analyses did not produce modifications in the direction or magnitude of the effect.
Authors' conclusions
The intervention evaluated in this meta-analysis does not have effects on pulmonary function but may influence exercise capacity, particularly VO(2) max. It is recommended to interpret the findings with caution due to the limited certainty of the available evidence.
Keywords: adult; non pharmacological intervention - psyco-soc-edu-org; Home; non pharmacological intervention - devices OR physiotherapy; Organization; training; Infection; Respiratory Tract Diseases;