CFDB - Cystic Fibrosis DataBase

primary studies published RCT

Assessment of medium-chain triglyceride feeding in infants with cystic fibrosis.

Study design (if review, criteria of inclusion for studies)



25 patients


Diets were randomly selected: 11 patients were given the MCT diet; 14 patients were used as controls.

Outcome measures

In all patients treated with MCT the stools became less frequent, bulky, and offensive. Using analysis of variance, no significant difference could be shown between chest scores and weight centiles for the MCT treated and 'control' groups at the end of the trial (p>0 1). Accelerated growth was shown to correlate well with effective treatment of pulmonary disease.

Keywords: Infant; Newborn; non pharmacological intervention - diet; Respiratory Tract Diseases; Supplementation;