CFDB - Cystic Fibrosis DataBase

primary studies published, non RCT

Assessment of in-line filters to prolong the life of intravenous cannulae in cystic fibrosis patients.

Participants

12 patients with cystic fibrosis

Interventions

replace the Venflon cannulae as they became non-patent and inserting a filter on alternate occasions. Thus each patient acted as her/his own control. 12 courses of intravenous antibiotics, each over 10-14 days, both with and without the use of an extended-life disposable filter

Outcome measures

times during which cannulae remained patent

Main results

Comparison of times during which cannulae remained patent showed a 50% improvement with use of a filter for 4 patients and no change for 7 patients. There was no significant difference associated with the use of a filter for the group as a whole but our small sample size excludes modest improvements.

Keywords: Adolescent; Adult; hydration; Hypertonic Solutions; Inhalation OR nebulised; non pharmacological intervention - devices OR physiotherapy; pharmacological_intervention; Anti-Bacterial Agents; Bacterial Infections; Infection; Respiratory Tract Infections; Intravenous; Respiratory System Agents; Respiratory Tract Diseases;