Study design (if review, criteria of inclusion for studies)
randomized trial
Participants
27 patients with cystic fibrosis, 17 had levels of alpha-tocopherol more than 2 SD below the mean.
Interventions
water-miscible form of vitamin E or a fat-soluble form for 6 months.
Outcome measures
vitamin E serum levels; cost
Main results
Either form was effective in achieving normal serum levels; the fat-soluble supplement has a significant cost advantage.