CFDB - Cystic Fibrosis DataBase

primary studies published RCT

Correction of vitamin E deficiency with fat-soluble versus water-miscible preparations of vitamin E in patients with cystic fibrosis.

Study design (if review, criteria of inclusion for studies)

randomized trial

Participants

27 patients with cystic fibrosis, 17 had levels of alpha-tocopherol more than 2 SD below the mean.

Interventions

water-miscible form of vitamin E or a fat-soluble form for 6 months.

Outcome measures

vitamin E serum levels; cost

Main results

Either form was effective in achieving normal serum levels; the fat-soluble supplement has a significant cost advantage.

Keywords: Adolescent; Adult; Child; non pharmacological intervention - diet; vitamins; Vitamin E; Vitamins; Antioxidants; pharmacological_intervention;