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ongoing trials trial from www.clinicaltrials.gov

Clinical trial of comparison between use of intravenous aminoglycosides versus intravenous and nebulize aminoglycosides in cystic fibrosis patients - Recruiting

  • Year: 2021
  • Date: June 29, 2021
  • Author:
Source

http://en.irct.ir/trial/55963

Study design (if review, criteria of inclusion for studies)

Interventional - Allocation: Randomized|Intervention Model: Parallel Assignment|Masking: Triple (Participant, Care Provider, Investigator)|Primary Purpose: Treatment

Participants

Cystic Fibrosis (CF) - 18 Years and older   (Adult, Older Adult)

Interventions

Drug: Galicaftor|Drug: Placebo|Drug: Navocaftor|Drug: ABBV-119

Outcome measures

Absolute Change From Baseline in ppFEV1|Absolute Change From Baseline in Sweat Chloride (SwCl)|Absolute Change From Baseline in Forced Vital Capacity [FVC]|Absolute Change From Baseline in Forced Expiratory Flow at Mid-Lung Capacity [FEF25-75]|Relative Changes From Baseline in ppFEV1|Relative Changes From Baseline in FVC|Relative Changes From Baseline in FEF25-75|Absolute Change in CF Questionnaire-Revised (CFQ-R) Respiratory Domain Score From Baseline

Keywords: Adult; Aminophenols; CFTR Modulators; Genetic Predisposition to Disease; pharmacological_intervention; Galicaftor; Navocaftor; ABBV119;