primary studies published RCT Bronchial response to nebulized antibiotics in children with cystic fibrosis. Year: 1990 Date: 1995 Author: Chua HL Source The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology YR: 1990 VL: 3 NO: 10 Study design (if review, criteria of inclusion for studies) single- and multiple-dose studies of beta-carotene supplementation in patients with CF Interventions beta-carotene supplementation Outcome measures beta-carotene concentrations, beta-carotene clearance Main results Dose-proportional increases in beta-carotene concentrations were found, although clearance was independent of dose. Authors' conclusions Large doses of beta-carotene were necessary to achieve normal plasma levels. Related topics A, E, K vitamins supplementation Vitamin D supplementation