primary studies published RCT Anti-RSV prophylaxis efficacy for infants and young children with cystic fibrosis in Ireland. Year: 2015 Date: 1983 Author: Linnane B Source Multidiscip Respir Med. 2015 Oct 15;10:32. doi: 10.1186/s40248-015-0029-9. eCollection 2015. Study design (if review, criteria of inclusion for studies) randomized trial Participants 16 adults with cystic fibrosis and chronic bronchopulmonary infection with Pseudomonas aeruginosa, admitted to hospital for chemotherapy Interventions carbenicillin or ticarcillin. In addition all patients received gentamicin. Outcome measures respiratory function, Pseudomonas aeruginosa eradication Main results Both antibiotic treatments produced clinical improvement and significant improvement in respiratory function, but there was no difference between them. Pseudomonas aeruginosa was not eradicated from sputum with either treatment regimen. Related topics Antibiotic treatment of early pseudomonas aeruginosa Antibiotics for pulmonary exacerbations Inhaled antibiotics in cystic fibrosis MRSA eradication in CF Prophylactic use of oral antistaphylococcal antibiotic Scheduled antibiotics every 3-4 months / symptom-based treatment