Study design (if review, criteria of inclusion for studies)
16 adults with cystic fibrosis and chronic bronchopulmonary infection with Pseudomonas aeruginosa, admitted to hospital for chemotherapy
carbenicillin or ticarcillin. In addition all patients received gentamicin.
respiratory function, Pseudomonas aeruginosa eradication
Both antibiotic treatments produced clinical improvement and significant improvement in respiratory function, but there was no difference between them. Pseudomonas aeruginosa was not eradicated from sputum with either treatment regimen.