CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2025
  • Calthorpe R

Non-invasive ventilation for cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2025
  • AS Sousa

Cystic fibrosis-related diabetes in the era of modern treatment using CFTR modulators in pediatric patients-a systematic review.

Other Reviews - Other Review

Details
  • 2025
  • Pietrzykowska A

Comparative efficacy and safety of CFTR modulators for people with cystic fibrosis with phe508del mutation: a systematic review and bayesian network meta-analysis.

Other Reviews - Other Review

Details
  • 2025
  • Safeer V S M

Impact of Elexacaftor/Tezacaftor/Ivacaftor on Glucose Tolerance and Abnormal Glucose Metabolism: A Phase 3b, Open-Label Clinical Trial.

primary studies published RCT

Details
  • 2025
  • Durieu I

Effectiveness of the hippotherapy simulator in children and adolescents with cystic fibrosis: A randomized controlled trial.

primary studies published RCT

Details
  • 2025
  • Cinar B

The Effect of Probiotic Consumption on Improving the Quality of Life in Children Aged 6 to 13 Years with Cystic Fibrosis (CF) - Pending

ongoing trials trial from other registries

Details
  • 2025