Welcome in CFDB (Cystic Fibrosis DataBase)!
This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.
You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.
Objective of CFDB (Cystic Fibrosis DataBase)
CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:
- which interventions are effective, in which groups of CF patients and for which outcomes?
- to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?
This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.
Latest articles
Antibiotic treatment for nonâtuberculous mycobacteria lung infection in people with cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2025
- Jahnke N
Examining the safety and efficacy of Azithromycin in Cystic fibrosis: A systematic review and Meta-analysis.
Other Reviews - Other Review
Details- 2025
- Elmegeed AA
Long-Term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Adults and Adolescents with Cystic Fibrosis and at Least One F508del Allele: A Phase 3, Open-Label Extension Study.
primary studies published RCT
Details- 2025
- Daines CL
Cannabinoid receptor 2 agonist, lenabasum, for the treatment of pulmonary exacerbations in cystic fibrosis.
primary studies published RCT
Details- 2025
- West NE
Randomized Cross-Over Analysis of the Influence of Nitrogen Multiple Breath Washout on Spirometry in Monitoring Lung Function in Patients With Cystic Fibrosis and Primary Ciliary Dyskinesia.
primary studies published RCT
Details- 2025
- Schoop AC
Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta
ongoing trials trial from www.clinicaltrials.gov
Details- 2025
Study With Phage for CF Subjects With Pseudomonas Lung Infection
ongoing trials trial from www.clinicaltrials.gov
Details- 2025