CFDB - Cystic Fibrosis DataBase

Welcome in CFDB (Cystic Fibrosis DataBase)!

This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.

You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.

Objective of CFDB (Cystic Fibrosis DataBase)

CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:

  • which interventions are effective, in which groups of CF patients and for which outcomes?
  • to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?

This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.

Latest articles

Antibiotic treatment for non‐tuberculous mycobacteria lung infection in people with cystic fibrosis

Cochrane Database of Systematic Reviews - Cochrane Review

Details
  • 2025
  • Jahnke N

Physical Training and Pulmonary Rehabilitation in Patients with Cystic Fibrosis: A Systematic Review and Meta-Analysis of Clinical Trials.

Other Reviews - Other Review

Details
  • 2025
  • Murillo SR

Effectiveness of nutritional intervention package versus conventional nutritional counseling in pediatric cystic fibrosis: A randomized controlled trial.

primary studies published RCT

Details
  • 2025
  • Sharma R

The Impact of Mandala Coloring on Anxiety of Children with Cystic Fibrosis: A Randomized Trial.

primary studies published RCT

Details
  • 2025
  • Omidi A

Evaluating Long-Term Effectiveness of Cystic Fibrosis Modulator Therapies After Rapid Adoption: A Dual-Approach Study.

primary studies published, non RCT

Details
  • 2025
  • Afonso PM

Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2025

Study With Phage for CF Subjects With Pseudomonas Lung Infection

ongoing trials trial from www.clinicaltrials.gov

Details
  • 2025