CFDB - Cystic Fibrosis DataBase

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Is a longer time interval between recombinant human deoxyribonuclease (dornase alfa) and chest physiotherapy better? A multi-center, randomized crossover trial.

primary studies  published RCT

Details
  • 2007
  • Wilson CJ

A prospective randomised controlled mixed-methods pilot study of home monitoring in adults with cystic fibrosis.

primary studies  published RCT

Details
  • 2022
  • Nash EF

Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials.

primary studies  published RCT

Details
  • 2022
  • Mayer-Hamblett N

Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection.

primary studies  published RCT

Details
  • 2022
  • Fischer R

Airway clearance physiotherapy and health-related quality of life in cystic fibrosis.

primary studies  published RCT

Details
  • 2022
  • Gursli S

Gut Bifidobacteria enrichment following oral Lactobacillus-supplementation is associated with clinical improvements in children with cystic fibrosis.

primary studies  published RCT

Details
  • 2022
  • Ray KJ

Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3B, Randomized, Placebo-Controlled Study.

primary studies  published RCT

Details
  • 2022
  • Mall MA

The effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial.

primary studies  published RCT

Details
  • 2022
  • Stick SM

Effect of airway clearance therapies on mucociliary clearance in adults with cystic fibrosis: A randomized controlled trial.

primary studies  published RCT

Details
  • 2022
  • Trimble A

"You're on mute!" Does pediatric CF home spirometry require physiologist supervision?

primary studies  published RCT

Details
  • 2022
  • Fettes E