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VO(2max) as an exercise tolerance endpoint in people with cystic fibrosis: Lessons from a lumacaftor/ivacaftor trial.
primary studies published RCT
Details- 2021
- Wilson J
A phase 3, double-blind, parallel-group study to evaluate the efficacy and safety of tezacaftor in combination with ivacaftor in participants 6 through 11 years of age with cystic fibrosis homozygous for F508del or heterozygous for the F508del-CFTR mutation and a residual function mutation.
primary studies published RCT
Details- 2021
- Davies JC
Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and Pseudomonas aeruginosa infection: the TORPEDO-CF RCT.
primary studies published RCT
Details- 2021
- Langton Hewer SC
Manuka honey versus saline sinus irrigation in the treatment of cystic fibrosis-associated chronic rhinosinusitis: A randomised pilot trial.
primary studies published RCT
Details- 2021
- Lee VS
Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial.
primary studies published RCT
Details- 2021
- Sutharsan S
Safety and pharmacokinetics of Roscovitine (Seliciclib) in cystic fibrosis patients chronically infected with Pseudomonas aeruginosa, a randomized, placebo-controlled study.
primary studies published RCT
Details- 2021
- Meijer L
Self-management intervention to reduce pulmonary exacerbations by supporting treatment adherence in adults with cystic fibrosis: a randomised controlled trial.
primary studies published RCT
Details- 2021
- Wildman MJ
Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.
primary studies published RCT
Details- 2021
- Barry PJ
Effects of a Partially Supervised Conditioning Program in Cystic Fibrosis: An International Multicenter Randomized Controlled Trial (ACTIVATE-CF).
primary studies published RCT
Details- 2021
- Hebestreit H
Interval versus constant-load exercise training in adults with Cystic Fibrosis.
primary studies published RCT
Details- 2021
- Kaltsakas G