Lumacaftor/Ivacaftor reduces pulmonary exacerbations in patients irrespective of initial changes in FEV1.
primary studies published RCT
Details- 2019
- McColley SA
Impact of hypertonic saline nebulisation combined with oscillatory positive expiratory pressure on sputum expectoration and related symptoms in cystic fibrosis: a randomised crossover trial.
primary studies published RCT
Details- 2019
- San Miguel-Pagola M
Exenatide corrects postprandial hyperglycaemia in young people with cystic fibrosis and impaired glucose tolerance: A randomized crossover trial.
primary studies published RCT
Details- 2019
- Geyer MC
Dornase alfa during lower respiratory tract infection post-lung transplantation: a randomized controlled trial.
primary studies published RCT
Details- 2019
- Tarrant BJ
Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.
primary studies published RCT
Details- 2019
- Heijerman HGM
Sildenafil improves exercise capacity in patients with cystic fibrosis: a proof-of-concept clinical trial.
primary studies published RCT
Details- 2019
- Rodriguez-Miguelez P
Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.
primary studies published RCT
Details- 2019
- Middleton PG
Airway clearance physiotherapy improves ventilatory dynamics during exercise in patients with cystic fibrosis: a pilot study.
primary studies published RCT
Details- 2019
- Vendrusculo FM
A smartphone application for reporting symptoms in adults with cystic fibrosis improves the detection of exacerbations: Results of a randomised controlled trial.
primary studies published RCT
Details- 2019
- Wood J
Inhaled hypertonic saline in preschool children with cystic fibrosis (SHIP): a multicentre, randomised, double-blind, placebo-controlled trial.
primary studies published RCT
Details- 2019
- Ratjen F