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Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials.
primary studies published RCT
Details- 2023
- Mayer-Hamblett N
Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection.
primary studies published RCT
Details- 2022
- Fischer R
Airway clearance physiotherapy and health-related quality of life in cystic fibrosis.
primary studies published RCT
Details- 2022
- Gursli S
Gut Bifidobacteria enrichment following oral Lactobacillus-supplementation is associated with clinical improvements in children with cystic fibrosis.
primary studies published RCT
Details- 2022
- Ray KJ
Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3B, Randomized, Placebo-Controlled Study.
primary studies published RCT
Details- 2022
- Mall MA
The effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial.
primary studies published RCT
Details- 2022
- Stick SM
Effect of airway clearance therapies on mucociliary clearance in adults with cystic fibrosis: A randomized controlled trial.
primary studies published RCT
Details- 2022
- Trimble A
"You're on mute!" Does pediatric CF home spirometry require physiologist supervision?
primary studies published RCT
Details- 2022
- Fettes E
Pilot RCT of a telehealth intervention to reduce symptoms of depression and anxiety in adults with cystic fibrosis.
primary studies published RCT
Details- 2022
- Bathgate CJ
Is exercise and electrostimulation effective in improving muscle strength and cardiorespiratory fitness in children with cystic fibrosis and mild-to-moderate pulmonary impairment?: Randomized controlled trial.
primary studies published RCT
Details- 2022
- Donadio MVF